Strategies for Tuning the Selectivity of Chemical Probes that Target Serine Hydrolases.

Faucher, Franco; Bennett, John M; Bogyo, Matthew; Lovell, Scott

Faucher, Franco; Bennett, John M; Bogyo, Matthew; Lovell, Scott.

Afiliación

Faucher F; Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
Bennett JM; Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
Bogyo M; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: mbogyo@stanford.edu.
Lovell S; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: slovell@stanford.edu.

Cell Chem Biol ; 27(8): 937-952, 2020 08 20.

Article en En | MEDLINE | ID: mdl-32726586

Asunto(s)

Colorantes Fluorescentes/química; Serina Proteasas/metabolismo; Química Clic; Colorantes Fluorescentes/metabolismo; Organofosfonatos/química; Organofosfonatos/metabolismo; Péptidos/química; Péptidos/metabolismo; Proteómica; Rodaminas/química; Rodaminas/metabolismo; Serina Proteasas/química; Bibliotecas de Moléculas Pequeñas/química; Bibliotecas de Moléculas Pequeñas/metabolismo

Palabras clave

activity-based probe; activity-based protein profiling; covalent binders; protease; serine hydrolase

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serina Proteasas / Colorantes Fluorescentes Idioma: En Revista: Cell Chem Biol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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