Effects of gut microbiome-targeted therapies on cardiometabolic outcomes in children and adolescents: A protocol for systematic review and meta-analysis.
Medicine (Baltimore)
; 99(31): e21612, 2020 Jul 31.
Article
en En
| MEDLINE
| ID: mdl-32756217
ABSTRACT
BACKGROUND:
Emerging evidence indicates the role of gut microbiota in the development of cardiovascular diseases. Thus, gut microbiota is increasingly recognized as a potential therapeutic target of cardiovascular disease. However, the effects of gut microbiome-targeted therapies on cardiometabolic outcomes in children and adolescents remain unclear.METHODS:
We plan to perform a systematic search from PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and Web of Science. Two authors will independently select the relevant studies and extract data according to a previously defined data extraction sheet. We will use the Stata 14.0 statistical software and RevMan V.5.3 software to conduct data analyses. RESULTS ANDCONCLUSION:
The results of this study will be published in a peer-reviewed journal and provide more evidence for the application of gut microbiome-targeted therapies in children and adolescents for the intervention of cardiovascular risk factors in clinical practice. PROTOCOL REGISTRATION NUMBER INPLASY202060050.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
/
Probióticos
/
Suplementos Dietéticos
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Simbióticos
Tipo de estudio:
Clinical_trials
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Guideline
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Risk_factors_studies
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Systematic_reviews
Límite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Revista:
Medicine (Baltimore)
Año:
2020
Tipo del documento:
Article
País de afiliación:
China