Development, characterization, and application of a 2-Compartment system to investigate the impact of pH inhomogeneities in large-scale CHO-based processes.

Paul, Katrin; Böttinger, Katharina; Mitic, Bernd M; Scherfler, Georg; Posch, Christoph; Behrens, Dirk; Huber, Christian G; Herwig, Christoph

Paul, Katrin; Böttinger, Katharina; Mitic, Bernd M; Scherfler, Georg; Posch, Christoph; Behrens, Dirk; Huber, Christian G; Herwig, Christoph.

Afiliación

Paul K; Institute of Chemical Environmental and Bioscience Engineering TU Wien Vienna Austria.
Böttinger K; Christian Doppler Laboratory for Mechanistic and Physiological Methods for Improved Bioprocesses TU Wien Vienna Austria.
Mitic BM; Department of Biosciences Bioanalytical Research Labs University of Salzburg Salzburg Austria.
Scherfler G; Christian Doppler Laboratory for Innovative Tools for Biosimilar Characterization University of Salzburg Salzburg Austria.
Posch C; Institute of Chemical Environmental and Bioscience Engineering TU Wien Vienna Austria.
Behrens D; Christian Doppler Laboratory for Mechanistic and Physiological Methods for Improved Bioprocesses TU Wien Vienna Austria.
Huber CG; Institute of Chemical Environmental and Bioscience Engineering TU Wien Vienna Austria.
Herwig C; Christian Doppler Laboratory for Mechanistic and Physiological Methods for Improved Bioprocesses TU Wien Vienna Austria.

Eng Life Sci ; 20(8): 368-378, 2020 Aug.

Article en En | MEDLINE | ID: mdl-32774209

Palabras clave

2Compartment system; CHO; inhomogeneities; largescale; pH excursions; scaledown

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Eng Life Sci Año: 2020 Tipo del documento: Article