[Morphologic demonstration of adsorption of Sonne shigellae onto intestinal epithelium]. / Morfologicheskoe proiavlenie adsorbtsii shigell Zonne na épitelii kishechnika.
Arkh Patol
; 39(4): 68-73, 1977.
Article
en Ru
| MEDLINE
| ID: mdl-327985
ABSTRACT
Electron-microscopy studies of the process of absorption of Shigella sonnei on the epithelium of the intestine villi of Syrian hamstes were carried out. In the study there were used 20 animals and 8 stains of Shigellae isolated from patients with acute dysentery. It was shown that in inoculating into an isolated loop of the intestine adhesion of Shigellae to the surface of border cells was accompanied by rearrangement of glycocalyx with subsequent destruction of microvilli in the zone of adsorption. Simultaneously, lysis of adsorbed bacteria occurred. An assumption is put forward that penetration of Shigellae into the epithelium is a multistaged process which is realised in the phase of adsorption not by one bacterium but by the whole pepulation with the help of soluable substances producing a toxic effect.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Shigella sonnei
/
Disentería Bacilar
/
Mucosa Intestinal
Límite:
Animals
/
Humans
Idioma:
Ru
Revista:
Arkh Patol
Año:
1977
Tipo del documento:
Article