Optimization of lipid materials in the formulation of S-carvedilol self-microemulsifying drug-delivery systems.

Zhang, Qi; Guo, Kunkun; Wang, Xin; Huang, Baolin; Lin, Zimin; Cai, Zheng

Zhang, Qi; Guo, Kunkun; Wang, Xin; Huang, Baolin; Lin, Zimin; Cai, Zheng.

Afiliación

Zhang Q; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, China.
Guo K; Institute of Materia Medica, Hangzhou Medical College, Hangzhou, China.
Wang X; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, China.
Huang B; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, China.
Lin Z; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, China.
Cai Z; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, China.

Drug Dev Ind Pharm ; 46(9): 1507-1516, 2020 Sep.

Article en En | MEDLINE | ID: mdl-32806972

Asunto(s)

Carvedilol/química; Sistemas de Liberación de Medicamentos; Lípidos; Administración Oral; Animales; Disponibilidad Biológica; Ratas; Solubilidad

Palabras clave

S-carvedilol; bioavailability; first-pass effect; lipid; self-microemulsifying drug-delivery system; solubility

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistemas de Liberación de Medicamentos / Carvedilol / Lípidos Límite: Animals Idioma: En Revista: Drug Dev Ind Pharm Año: 2020 Tipo del documento: Article País de afiliación: China

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