Exercise-induced calf muscle hyperemia: Rapid mapping of magnetic resonance imaging using deep learning approach.
Physiol Rep
; 8(16): e14563, 2020 08.
Article
en En
| MEDLINE
| ID: mdl-32812401
ABSTRACT
Exercise-induced hyperemia in calf muscles was recently shown to be quantifiable with high-resolution magnetic resonance imaging (MRI). However, processing of the MRI data to obtain muscle-perfusion maps is time-consuming. This study proposes to substantially accelerate the mapping of muscle perfusion using a deep-learning method called artificial neural network (NN). Forty-eight MRI scans were acquired from 21 healthy subjects and patients with peripheral artery disease (PAD). For optimal training of NN, different training-data sets were compared, investigating the effect of data diversity and reference perfusion accuracy. Reference perfusion was estimated by tracer kinetic model fitting initialized with multiple values (multigrid model fitting). Result:
The NN method was much faster than tracer kinetic model fitting. To generate a perfusion map of matrix 128 × 128 on a same computer, multigrid model fitting took about 80 min, single-grid or regular model fitting about 3 min, while the NN method took about 1 s. Compared to the reference values, NN trained with a diverse group gave estimates with mean absolute error (MAE) of 15.9 ml/min/100g and correlation coefficient (R) of 0.949, significantly more accurate than regular model fitting (MAE 22.3 ml/min/100g, R 0.889, p < .001).Conclusion:
the NN method enables rapid perfusion mapping, and if properly trained, estimates perfusion with accuracy comparable to multigrid model fitting.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Imagen por Resonancia Magnética
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Ejercicio Físico
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Músculo Esquelético
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Imagen de Perfusión
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Enfermedad Arterial Periférica
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Hiperemia
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Physiol Rep
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos