Uveitis, retinal vasculitis, and loss of accommodation as sole manifestations of demyelinating disease: A case report.
Indian J Ophthalmol
; 68(9): 2007-2009, 2020 Sep.
Article
en En
| MEDLINE
| ID: mdl-32823460
In this report we describe nongranulomatous uveitis followed by bilateral retinal vasculitis and much later by the loss of accommodation as initial presentations of demyelinating disease in a 42-year-old female with no other neurologic manifestations. The absence of demyelinating plaques in the initial magneric resonance imaging (MRI) (orbit and cranium) and its occurrence 2 years later, have been described as "lesions appearing with time". Extensive laboratory investigations ruled out infections, systemic vasculitis, and connective tissue disorders. Due to the presence of oligoclonal bands in both cerebrospinal fluid (CSF) and serum, absence of antiaquaporin-4, antimyelin-oligodendrocyte glycoprotein immunoglobulin G (IgG) antibodies, and negative vasculitis profile, the exact cause of demyelination (multiple sclerosis/vasculitis related) could not be ascertained. She has currently received 2 cycles of rituximab and at the last follow-up did not show any recurrences.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Uveítis
/
Vasculitis Retiniana
/
Esclerosis Múltiple
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Adult
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Female
/
Humans
Idioma:
En
Revista:
Indian J Ophthalmol
Año:
2020
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
India