On the roles of calcium and zinc ions in the formation of a catalytically active form of the metalloenzyme, l-alanyl-d-glutamate peptidase of the bacteriophage T5 (EndoT5).

Kutyshenko, Victor P; Mikoulinskaia, Galina V; Prokhorov, Dmitry A; Molochkov, Nikolai V; Yegorov, Alexander Y; Uversky, Vladimir N

Kutyshenko, Victor P; Mikoulinskaia, Galina V; Prokhorov, Dmitry A; Molochkov, Nikolai V; Yegorov, Alexander Y; Uversky, Vladimir N.

Afiliación

Kutyshenko VP; Institute of Theoretical and Experimental Biophysics, RAS, Pushchino, Moscow Region 142290, Russia. Electronic address: kutyshenko@rambler.ru.
Mikoulinskaia GV; Branch of Shemyakin & Ovchinnikov's Institute of Bioorganic Chemistry, RAS, Pushchino, Moscow Region 142290, Russia. Electronic address: mikulinskaya@bibch.ru.
Prokhorov DA; Institute of Theoretical and Experimental Biophysics, RAS, Pushchino, Moscow Region 142290, Russia.
Molochkov NV; Institute of Theoretical and Experimental Biophysics, RAS, Pushchino, Moscow Region 142290, Russia.
Yegorov AY; Institute of Theoretical and Experimental Biophysics, RAS, Pushchino, Moscow Region 142290, Russia. Electronic address: a.egorov@vega.protres.ru.
Uversky VN; Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA; Laboratory of New Methods in Biology, Institute for Biological Instrumentation of the Russian Academy of Sciences, Federal Research Center "P

Int J Biol Macromol ; 164: 2711-2716, 2020 Dec 01.

Article en En | MEDLINE | ID: mdl-32841672

Asunto(s)

Bacteriófago T7/enzimología; Calcio/metabolismo; Endopeptidasas/química; Endopeptidasas/metabolismo; Proteínas Virales/química; Proteínas Virales/metabolismo; Zinc/metabolismo; Sustitución de Aminoácidos; Bacteriófago T7/genética; Dominio Catalítico; Endopeptidasas/genética; Activación Enzimática; Iones/metabolismo; Espectroscopía de Resonancia Magnética; Modelos Moleculares; Unión Proteica; Conformación Proteica; Proteínas Virales/genética

Palabras clave

EndoT5; Metal-binding protein; NMR

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endopeptidasas / Proteínas Virales / Zinc / Calcio / Bacteriófago T7 Tipo de estudio: Prognostic_studies Idioma: En Revista: Int J Biol Macromol Año: 2020 Tipo del documento: Article Pais de publicación: Países Bajos

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