Formulations for Allergen Immunotherapy in Human and Veterinary Patients: New Candidates on the Horizon.
Front Immunol
; 11: 1697, 2020.
Article
en En
| MEDLINE
| ID: mdl-32849594
ABSTRACT
Allergen immunotherapy is currently the only causal treatment for allergic diseases in human beings and animals. It aims to re-direct the immune system into a tolerogenic or desensitized state. Requirements include clinical efficacy, safety, and schedules optimizing patient or owner compliance. To achieve these goals, specific allergens can be formulated with adjuvants that prolong tissue deposition and support uptake by antigen presenting cells, and/or provide a beneficial immunomodulatory action. Here, we depict adjuvant formulations being investigated for human and veterinary allergen immunotherapy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Alérgenos
/
Adyuvantes Inmunológicos
/
Desensibilización Inmunológica
/
Drogas Veterinarias
/
Hipersensibilidad
/
Tolerancia Inmunológica
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Front Immunol
Año:
2020
Tipo del documento:
Article
País de afiliación:
Austria