Exoproteomics for Better Understanding Pseudomonas aeruginosa Virulence.
Toxins (Basel)
; 12(9)2020 09 04.
Article
en En
| MEDLINE
| ID: mdl-32899849
ABSTRACT
Pseudomonas aeruginosa is the most common human opportunistic pathogen associated with nosocomial diseases. In 2017, the World Health Organization has classified P. aeruginosa as a critical agent threatening human health, and for which the development of new treatments is urgently necessary. One interesting avenue is to target virulence factors to understand P. aeruginosa pathogenicity. Thus, characterising exoproteins of P. aeruginosa is a hot research topic and proteomics is a powerful approach that provides important information to gain insights on bacterial virulence. The aim of this review is to focus on the contribution of proteomics to the studies of P. aeruginosa exoproteins, highlighting its relevance in the discovery of virulence factors, post-translational modifications on exoproteins and host-pathogen relationships.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pseudomonas aeruginosa
/
Proteínas Bacterianas
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Proteoma
/
Factores de Virulencia
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Proteómica
Idioma:
En
Revista:
Toxins (Basel)
Año:
2020
Tipo del documento:
Article
País de afiliación:
Francia