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3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants.
Luis, Eric; Pan, Houwen Matthew; Bastola, Anil Kumar; Bajpai, Ram; Sing, Swee Leong; Song, Juha; Yeong, Wai Yee.
Afiliación
  • Luis E; Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Drive, Singapore 639798, Singapore.
  • Pan HM; School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 639798, Singapore.
  • Bastola AK; Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Drive, Singapore 639798, Singapore.
  • Bajpai R; Center for Population Health Sciences, Lee Kong Chien School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore 308232, Singapore.
  • Sing SL; Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Drive, Singapore 639798, Singapore.
  • Song J; School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 639798, Singapore.
  • Yeong WY; Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Drive, Singapore 639798, Singapore.
Polymers (Basel) ; 12(9)2020 Sep 18.
Article en En | MEDLINE | ID: mdl-32962059
Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and are not mechanically robust enough for human implantation. Similarly, 3D printed hydrogel scaffolds suffer from drawbacks of being mechanically weak and as a result patients are unable to execute immediate post-surgical weight-bearing ambulation and rehabilitation. To solve this problem, we have developed a 3D silicone meniscus implant which is (1) cytocompatible, (2) resistant to cyclic loading and mechanically similar to native meniscus, and (3) directly 3D printable. The main focus of this study is to determine whether the purity, composition, structure, dimensions and mechanical properties of silicone implants are affected by the use of a custom-made in-house 3D-printer. We have used the phosphate buffer saline (PBS) absorption test, Fourier transform infrared (FTIR) spectroscopy, surface profilometry, thermo-gravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM) to effectively assess and compare material properties between molded and 3D printed silicone samples.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Polymers (Basel) Año: 2020 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Polymers (Basel) Año: 2020 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Suiza