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pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model.
Xu, Xiaohong; Ng, Bryan; Sim, Bernice; Radulescu, Carola I; Yusof, Nur Amirah Binte Mohammad; Goh, Wah Ing; Lin, Shuping; Lim, John Soon Yew; Cha, Yoonjeong; Kusko, Rebecca; Kay, Chris; Ratovitski, Tamara; Ross, Christopher; Hayden, Michael R; Wright, Graham; Pouladi, Mahmoud A.
Afiliación
  • Xu X; Department of Neurology and Stroke Center, Clinical Neuroscience Institute, The First Affiliated Hospital, Jinan University, 613 Huangpu Avenue West, Guangzhou, Guangdong, 510632, China.
  • Ng B; Translational Laboratory in Genetic Medicine, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
  • Sim B; Translational Laboratory in Genetic Medicine, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
  • Radulescu CI; Translational Laboratory in Genetic Medicine, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
  • Yusof NABM; Translational Laboratory in Genetic Medicine, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
  • Goh WI; Translational Laboratory in Genetic Medicine, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
  • Lin S; Institute of Medical Biology, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
  • Lim JSY; Institute of Medical Biology, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
  • Cha Y; Institute of Medical Biology, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
  • Kusko R; Immuneering Corporation, 157 Columbus Avenue, Suite 537, New York, NY, 10023, USA.
  • Kay C; Immuneering Corporation, 157 Columbus Avenue, Suite 537, New York, NY, 10023, USA.
  • Ratovitski T; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, V5Z4H4, Canada.
  • Ross C; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Hayden MR; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Wright G; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, V5Z4H4, Canada.
  • Pouladi MA; Institute of Medical Biology, 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.
Cell Death Dis ; 11(9): 809, 2020 09 25.
Article en En | MEDLINE | ID: mdl-32978366
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Células Madre Pluripotentes Inducidas / Mitocondrias Límite: Animals / Humans Idioma: En Revista: Cell Death Dis Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Células Madre Pluripotentes Inducidas / Mitocondrias Límite: Animals / Humans Idioma: En Revista: Cell Death Dis Año: 2020 Tipo del documento: Article País de afiliación: China