Single-cell transcriptome profiling reveals the mechanism of abnormal proliferation of epithelial cells in congenital cystic adenomatoid malformation.

Zhang, Shouhua; Ye, Chunjing; Xiao, Juhua; Yang, Jiale; Zhu, Chunhui; Xiao, Yu; Ye, Ming; Chen, Qiang

Zhang, Shouhua; Ye, Chunjing; Xiao, Juhua; Yang, Jiale; Zhu, Chunhui; Xiao, Yu; Ye, Ming; Chen, Qiang.

Afiliación

Zhang S; Department of General Surgery, Jiangxi Provincial Children's Hospital, Jiangxi, China; Department of Pediatrics, The Affiliated Children's Hospital of Nanchang University, Jiangxi, China.
Ye C; Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, China.
Xiao J; Department of Ultrasound, Jiangxi Provincial Maternal and Child Health Hospital, Jiangxi, China.
Yang J; Department of Pediatrics, The Affiliated Children's Hospital of Nanchang University, Jiangxi, China.
Zhu C; Department of General Surgery, Jiangxi Provincial Children's Hospital, Jiangxi, China; Department of Pediatrics, The Affiliated Children's Hospital of Nanchang University, Jiangxi, China.
Xiao Y; Department of General Surgery, Jiangxi Provincial Children's Hospital, Jiangxi, China; Department of Pediatrics, The Affiliated Children's Hospital of Nanchang University, Jiangxi, China.
Ye M; Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, China. Electronic address: yemyeming@163.com.
Chen Q; Department of General Surgery, Jiangxi Provincial Children's Hospital, Jiangxi, China; Department of Pediatrics, The Affiliated Children's Hospital of Nanchang University, Jiangxi, China. Electronic address: jx-cq@163.com.

Exp Cell Res ; 396(2): 112299, 2020 11 15.

Article en En | MEDLINE | ID: mdl-32979365

Asunto(s)

Malformación Adenomatoide Quística Congénita del Pulmón/genética; Malformación Adenomatoide Quística Congénita del Pulmón/patología; Células Epiteliales/metabolismo; Células Epiteliales/patología; Perfilación de la Expresión Génica; Análisis de la Célula Individual; Células Epiteliales Alveolares/metabolismo; Células Epiteliales Alveolares/patología; Linaje de la Célula/genética; Proliferación Celular/genética; Preescolar; Humanos; Pulmón/metabolismo; Pulmón/patología; Mastocitos/metabolismo

Palabras clave

Congenital cystic adenomatoid malformation; FGFR2; HBEGF; Proliferation; Single-cell RNA sequencing

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malformación Adenomatoide Quística Congénita del Pulmón / Perfilación de la Expresión Génica / Células Epiteliales / Análisis de la Célula Individual Límite: Child, preschool / Humans Idioma: En Revista: Exp Cell Res Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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