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Human diamine oxidase cellular binding and internalization in vitro and rapid clearance in vivo are not mediated by N-glycans but by heparan sulfate proteoglycan interactions.
Gludovacz, Elisabeth; Schuetzenberger, Kornelia; Resch, Marlene; Tillmann, Katharina; Petroczi, Karin; Vondra, Sigrid; Vakal, Serhii; Schosserer, Markus; Virgolini, Nikolaus; Pollheimer, Jürgen; Salminen, Tiina A; Jilma, Bernd; Borth, Nicole; Boehm, Thomas.
Afiliación
  • Gludovacz E; Department of Biotechnology, University of Natural Resources and Life Sciences, Muthgasse 18, Vienna 1190, Austria.
  • Schuetzenberger K; Department of Clinical Pharmacology, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
  • Resch M; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
  • Tillmann K; Department of Clinical Pharmacology, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
  • Petroczi K; Center for Biomedical Research, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
  • Vondra S; Department of Clinical Pharmacology, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
  • Vakal S; Department of Obstetrics and Gynecology, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
  • Schosserer M; Structural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, Tykistökatu 6A, Turku 20520, Finland.
  • Virgolini N; Department of Biotechnology, University of Natural Resources and Life Sciences, Muthgasse 18, Vienna 1190, Austria.
  • Pollheimer J; Department of Biotechnology, University of Natural Resources and Life Sciences, Muthgasse 18, Vienna 1190, Austria.
  • Salminen TA; Department of Obstetrics and Gynecology, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
  • Jilma B; Structural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, Tykistökatu 6A, Turku 20520, Finland.
  • Borth N; Department of Clinical Pharmacology, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
  • Boehm T; Department of Biotechnology, University of Natural Resources and Life Sciences, Muthgasse 18, Vienna 1190, Austria.
Glycobiology ; 31(4): 444-458, 2021 05 03.
Article en En | MEDLINE | ID: mdl-32985651
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Amina Oxidasa (conteniendo Cobre) / Proteoglicanos de Heparán Sulfato Límite: Animals / Humans Idioma: En Revista: Glycobiology Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Amina Oxidasa (conteniendo Cobre) / Proteoglicanos de Heparán Sulfato Límite: Animals / Humans Idioma: En Revista: Glycobiology Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Reino Unido