MiR-181a enhances drug sensitivity of mixed lineage leukemia-rearranged acute myeloid leukemia by increasing poly(ADP-ribose) polymerase1 acetylation.

Zhou, Di; Xu, Peipei; Zhou, Xuan; Diao, Zhenyu; Ouyang, Jian; Yan, Guijun; Chen, Bing

Zhou, Di; Xu, Peipei; Zhou, Xuan; Diao, Zhenyu; Ouyang, Jian; Yan, Guijun; Chen, Bing.

Afiliación

Zhou D; Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.
Xu P; Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.
Zhou X; Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.
Diao Z; Department of Reproductive Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.
Ouyang J; Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.
Yan G; Department of Reproductive Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.
Chen B; Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.

Leuk Lymphoma ; 62(1): 136-146, 2021 01.

Article en En | MEDLINE | ID: mdl-32996365

Asunto(s)

Leucemia Mieloide Aguda; MicroARNs; Preparaciones Farmacéuticas; Acetilación; Humanos; Leucemia Mieloide Aguda/tratamiento farmacológico; Leucemia Mieloide Aguda/genética; MicroARNs/genética; MicroARNs/metabolismo; Proteína de la Leucemia Mieloide-Linfoide/genética; Poli Adenosina Difosfato Ribosa

Palabras clave

AML; PARP1; Sirt1; acetylation; miR-181a

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Leucemia Mieloide Aguda / MicroARNs Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Leuk Lymphoma Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos

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