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Delayed matching to sample task 48: assessment of malingering with simulating design.
Nikolai, T; Cechova, K; Bukacova, K; Fendrych Mazancova, A; Markova, H; Bezdicek, O; Hort, J; Vyhnalek, M.
Afiliación
  • Nikolai T; Department of Neurology, Neuropsychology Laboratory, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.
  • Cechova K; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
  • Bukacova K; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
  • Fendrych Mazancova A; Department of Neurology, Memory Clinic, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Markova H; Department of Neurology, Neuropsychology Laboratory, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.
  • Bezdicek O; Department of Neurology, Neuropsychology Laboratory, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.
  • Hort J; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
  • Vyhnalek M; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
Article en En | MEDLINE | ID: mdl-32998629
ABSTRACT
The results of neuropsychological tests may be distorted by patients who exaggerate cognitive deficits. Eighty-three patients with cognitive deficit [Amnestic Mild Cognitive Impairment (aMCI), n = 53; Alzheimer's disease (AD) dementia, n = 30], 44 healthy older adults (HA), and 30 simulators of AD (s-AD) underwent comprehensive neuropsychological assessment. Receiver Operating Characteristic (ROC) analysis revealed high specificity but low sensitivity of the Delayed Matching to Sample Task (DMS48) in differentiating s-AD from AD dementia (87 and 53%, respectively) and from aMCI (96 and 57%). The sensitivity was considerably increased by using the DMS48/Rey Auditory Verbal Learning Test (RAVLT) ratio (specificity and sensitivity 93% and 93% for AD dementia and 96% and 80% for aMCI). The DMS48 differentiates s-AD from both aMCI and AD dementia with high specificity but low sensitivity. Its predictive value greatly increased when evaluated together with the RAVLT.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos del Conocimiento / Enfermedad de Alzheimer / Disfunción Cognitiva Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Aged / Humans Idioma: En Revista: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn Asunto de la revista: PSICOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos del Conocimiento / Enfermedad de Alzheimer / Disfunción Cognitiva Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Aged / Humans Idioma: En Revista: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn Asunto de la revista: PSICOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA