Clinical manifestations and laboratory results of 61 children with infectious mononucleosis.
J Int Med Res
; 48(10): 300060520924550, 2020 Oct.
Article
en En
| MEDLINE
| ID: mdl-33045888
ABSTRACT
OBJECTIVE:
To investigate the clinical manifestations of infectious mononucleosis in children of different ages.METHODS:
Clinical data from pediatric patients with infectious mononucleosis admitted from May 2015 to April 2019 were retrospectively analyzed. Patients were stratified into three groups (age 1-3 years, 4-6 years, and 7-14 years) for analysis of clinical and laboratory results.RESULTS:
Data from 61 patients (malefemale ratio 1.181) aged 5.15 ± 2.93 years (mean ± standard deviation; range 1-14 years) were analyzed. Infectious mononucleosis occurred throughout the year and the main clinical manifestations were fever (98.3%), tonsillitis (100%), tonsillar white exudate (83.6%), cervical lymphadenopathy (98.3%), hepatomegaly (37.7%), splenomegaly (42.6%), eyelid edema (41.0%), and nasal obstruction (49.2%). Disease onset was most common during early childhood (37.7%) and at preschool age (37.7%). Younger children had more obvious symptoms of nasal obstruction and older children had more significant elevations of alanine aminotransferase and higher percentages of atypical lymphocytes.CONCLUSION:
The clinical manifestations of infectious mononucleosis in children differed by age. These associations required attention for clinical decision making.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Mononucleosis Infecciosa
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Revista:
J Int Med Res
Año:
2020
Tipo del documento:
Article
País de afiliación:
China