Your browser doesn't support javascript.
loading
A prospective randomized study comparing bipolar plasmakinetic transurethral resection of the prostate and monopolar transurethral resection of the prostate for the treatment of Benign Prostatic Hyperplasia: efficacy, sexual function, Quality of Life, and complications.
Otaola-Arca, Hugo; Álvarez-Ardura, Manuel; Molina-Escudero, Roberto; Fernández, Mario I; Páez-Borda, Álvaro.
Afiliación
  • Otaola-Arca H; Department of Urology, Clínica Alemana, Santiago, Chile.
  • Álvarez-Ardura M; Department of Urology, Hospital Universitario de Fuenlabrada, Madrid, Spain.
  • Molina-Escudero R; International Doctoral School, Universidad Rey Juan Carlos, Madrid, Spain.
  • Fernández MI; Faculty of Medicine, Clínica Alemena-Universidad del Desarrollo, Santiago, Chile.
  • Páez-Borda Á; Department of Urology, Hospital Universitario de Fuenlabrada, Madrid, Spain.
Int Braz J Urol ; 47(1): 131-144, 2021.
Article en En | MEDLINE | ID: mdl-33047918
OBJECTIVE: To generate high-quality data comparing the clinical efficacy and safety profile between monopolar transurethral resection of the prostate (M-TURP) and bipolar plasmakinetic resection of the prostate (PK-TURP) for benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Prospective, randomized, single-blinded study conducted in a tertiary-care public institution (Dec/2014-Aug/2016). INCLUSION CRITERIA: prostate of <80g in patients with drug-refractory lower urinary tract symptoms (LUTS), complications derived from BPH, or both. EXCLUSION CRITERIA: a history of pelvic surgery/radiotherapy, neurogenic bladder dysfunction or documented/suspected prostate carcinoma. Treatment efficacy evaluated at 1, 3, 6 and 12 months. Efficacy outcomes: international prostate symptom score (IPSS), quality-of-life (QoL) score, international index of erectile function-5 (IIEF-5), maximum urinary flow rate (Qmax), postvoid residual urine (PVRU) volume, and prostate volume (PV). Complications and sequelae also assessed. Comparisons performed with parametric/non-parametric tests. RESULTS: Out of the 100 hundred patients, 84 qualified for the analysis (45 M-TURP/39 PK-TURP). No significant differences found in baseline characteristics or operative data, except for a longer operative time in PK-TURP (MD:7.9min; 95%CI:0.13-15.74; p=0.04). No differences found in IPSS, Qmax or PVRU volume. QoL score at 12 months was higher in PK-TURP (MD:0,9points; 95%CI:0.18-1.64; p=0.01). No differences in sexual function, PV, complications or sequelae were found. This study is "rigorous" (Jadad-scale) and has a low risk of bias (Cochrane-Handbook). CONCLUSIONS: Based on this controlled trial, there is not significant variation in effectiveness and safety between M-TURP and PK-TURP for the treatment of BPH. The small difference in QoL between PK-TURP and M-TURP at the one-year follow-up is not perceivable by the patients and, therefore, not clinically relevant.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hiperplasia Prostática / Resección Transuretral de la Próstata Tipo de estudio: Clinical_trials / Observational_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Humans / Male Idioma: En Revista: Int Braz J Urol Asunto de la revista: UROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Chile Pais de publicación: Brasil

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hiperplasia Prostática / Resección Transuretral de la Próstata Tipo de estudio: Clinical_trials / Observational_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Humans / Male Idioma: En Revista: Int Braz J Urol Asunto de la revista: UROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Chile Pais de publicación: Brasil