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Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits.
Böhme, Julia; Martinez, Nuria; Li, Shamin; Lee, Andrea; Marzuki, Mardiana; Tizazu, Anteneh Mehari; Ackart, David; Frenkel, Jessica Haugen; Todd, Alexandra; Lachmandas, Ekta; Lum, Josephine; Shihui, Foo; Ng, Tze Pin; Lee, Bernett; Larbi, Anis; Netea, Mihai G; Basaraba, Randall; van Crevel, Reinout; Newell, Evan; Kornfeld, Hardy; Singhal, Amit.
Afiliación
  • Böhme J; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Martinez N; Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA.
  • Li S; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Lee A; Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA.
  • Marzuki M; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Tizazu AM; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Ackart D; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Frenkel JH; Department of Microbiology, Immunology & Pathology, Colorado State University, Fort Collins, CO, 80525-1601, USA.
  • Todd A; Department of Microbiology, Immunology & Pathology, Colorado State University, Fort Collins, CO, 80525-1601, USA.
  • Lachmandas E; Department of Microbiology, Immunology & Pathology, Colorado State University, Fort Collins, CO, 80525-1601, USA.
  • Lum J; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.
  • Shihui F; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Ng TP; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Lee B; Gerontology Research Programme, Yong Loo Lin School of Medicine, Department of Psychological Medicine, National University Health System, National University of Singapore, Singapore, Singapore.
  • Larbi A; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Netea MG; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
  • Basaraba R; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.
  • van Crevel R; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany.
  • Newell E; Department of Microbiology, Immunology & Pathology, Colorado State University, Fort Collins, CO, 80525-1601, USA.
  • Kornfeld H; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.
  • Singhal A; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
Nat Commun ; 11(1): 5225, 2020 10 16.
Article en En | MEDLINE | ID: mdl-33067434
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Diabetes Mellitus Tipo 2 / Hipoglucemiantes / Metformina Tipo de estudio: Etiology_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Diabetes Mellitus Tipo 2 / Hipoglucemiantes / Metformina Tipo de estudio: Etiology_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Reino Unido