A Potential Role for IL-4 and IL-13 in an Alopecia Areata-Like Phenotype: A Clinical Perspective.

Marks, Dustin H; Senna, Maryanne M

Marks, Dustin H; Senna, Maryanne M.

Afiliación

Marks DH; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Senna MM; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Dermatology, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: msenna@partners.org.

J Investig Dermatol Symp Proc ; 20(1): S58-S59, 2020 11.

Article en En | MEDLINE | ID: mdl-33099387

ABSTRACT

ABSTRACT

Although alopecia areata (AA) has been traditionally classified as a strictly T helper type 1-mediated process, the T helper type 2 (Th2) pathway may contribute to an AA-like phenotype in some individuals. Herein, we describe three clinical cases that support the potential role of Th2 activity through the upregulation of IL-4 and IL-13 in an AA-like phenotype.

Asunto(s)

Alopecia Areata/inmunología; Alopecia Areata/metabolismo; Hipersensibilidad a los Alimentos/inmunología; Interleucina-13/metabolismo; Interleucina-4/metabolismo; Adolescente; Adulto; Alopecia Areata/complicaciones; Alopecia Areata/tratamiento farmacológico; Dermatitis Atópica/complicaciones; Dermatitis Atópica/tratamiento farmacológico; Femenino; Hipersensibilidad a los Alimentos/complicaciones; Preparaciones para el Cabello/efectos adversos; Humanos; Fenotipo; Células Th2; Adulto Joven

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interleucina-4 / Interleucina-13 / Alopecia Areata / Hipersensibilidad a los Alimentos Límite: Adolescent / Adult / Female / Humans Idioma: En Revista: J Investig Dermatol Symp Proc Asunto de la revista: DERMATOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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