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Sn(IV) N-confused porphyrins as photosensitizer dyes for photodynamic therapy in the near IR region.
Babu, Balaji; Mack, John; Nyokong, Tebello.
Afiliación
  • Babu B; Institute for Nanotechnology Innovation. Department of Chemistry, Rhodes University, Makhanda, South Africa.
  • Mack J; Institute for Nanotechnology Innovation. Department of Chemistry, Rhodes University, Makhanda, South Africa.
  • Nyokong T; Institute for Nanotechnology Innovation. Department of Chemistry, Rhodes University, Makhanda, South Africa.
Dalton Trans ; 49(43): 15180-15183, 2020 Nov 10.
Article en En | MEDLINE | ID: mdl-33107524
ABSTRACT
The utility of Sn(iv) N-confused porphyrin (SnNCP) for use as photosensitizer dyes in photodynamic therapy is investigated. SnNCP has an unusually high singlet oxygen quantum yield of 0.72 in DMSO. IC50 values of 1.6 and 12.8 µM were obtained against MCF-7 cells upon irradiation with 660 and 780 nm LEDs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / Porfirinas / Estaño / Fármacos Fotosensibilizantes / Colorantes Límite: Humans Idioma: En Revista: Dalton Trans Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Sudáfrica
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / Porfirinas / Estaño / Fármacos Fotosensibilizantes / Colorantes Límite: Humans Idioma: En Revista: Dalton Trans Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Sudáfrica