[Disorders in the thrombocyte link of hemostasis during endotoxinemia and their correction with the inhibitor of prostaglandin biosynthesis, indomethacin]. / Narusheniia v trombotsitarnom zvene gemostaza pri éndotoksinemii i korrektsiia ikh ingibitorom biosinteza prostaglandinov, indometatsinom.
Nauchnye Doki Vyss Shkoly Biol Nauki
; (7): 68-72, 1987.
Article
en Ru
| MEDLINE
| ID: mdl-3311179
ABSTRACT
After 10 minutes of endotoxin Salmonella typhimurium (1 mg/kg) injection into rabbits thrombocytopenia appeared, the aggregation and secretory function of circulating platelets reduced, the transformation of platelet forms from disk-shaped into spheroidal took place. On the surface of plasmatic membranes the pseudopodies and aggregates examining samples of PRP were observed. Indomethacin, blockator of biosynthesis of prostaglandins results in normalisation of morphofunctional properties of platelets.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Salmonella typhimurium
/
Agregación Plaquetaria
/
Indometacina
/
Endotoxinas
/
Trombocitemia Esencial
Tipo de estudio:
Etiology_studies
Límite:
Animals
Idioma:
Ru
Revista:
Nauchnye Doki Vyss Shkoly Biol Nauki
Año:
1987
Tipo del documento:
Article