Aging-Related Phenotypic Conversion of Medullary Microglia Enhances Intraoral Incisional Pain Sensitivity.

Ikutame, Daisuke; Urata, Kentaro; Oto, Tatsuki; Fujiwara, Shintaro; Iinuma, Toshimitsu; Shibuta, Ikuko; Hayashi, Yoshinori; Hitomi, Suzuro; Iwata, Koichi; Shinoda, Masamichi

Ikutame, Daisuke; Urata, Kentaro; Oto, Tatsuki; Fujiwara, Shintaro; Iinuma, Toshimitsu; Shibuta, Ikuko; Hayashi, Yoshinori; Hitomi, Suzuro; Iwata, Koichi; Shinoda, Masamichi.

Afiliación

Ikutame D; Department of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Urata K; Department of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Oto T; Department of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Fujiwara S; Department of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Iinuma T; Department of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Shibuta I; Department of Physiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Hayashi Y; Department of Physiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Hitomi S; Department of Physiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Iwata K; Department of Physiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Shinoda M; Department of Physiology, Nihon University School of Dentistry, Tokyo 101-8310, Japan.

Int J Mol Sci ; 21(21)2020 Oct 23.

Article en En | MEDLINE | ID: mdl-33114176

Asunto(s)

Envejecimiento/inmunología; Dolor Facial/inmunología; Interleucina-10/metabolismo; Microglía/inmunología; Factor de Necrosis Tumoral alfa/metabolismo; Animales; Antígenos CD/metabolismo; Antígenos de Diferenciación Mielomonocítica/metabolismo; Antígenos CD11/metabolismo; Modelos Animales de Enfermedad; Dolor Facial/etiología; Masculino; Ratones; Fenotipo; Receptores de Superficie Celular/metabolismo; Transducción de Señal

Palabras clave

IL-10; M1; M2; SAMP8; SAMR1; TNF-α; intraoral incision; microglia; orofacial mechanical allodynia; senescence-accelerated mice

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Facial / Envejecimiento / Factor de Necrosis Tumoral alfa / Interleucina-10 / Microglía Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Japón

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