Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase.

Smith, Kyle P; Focia, Pamela J; Chakravarthy, Srinivas; Landahl, Eric C; Klosowiak, Julian L; Rice, Sarah E; Freymann, Douglas M

Smith, Kyle P; Focia, Pamela J; Chakravarthy, Srinivas; Landahl, Eric C; Klosowiak, Julian L; Rice, Sarah E; Freymann, Douglas M.

Afiliación

Smith KP; Department of Cell & Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA. Electronic address: kyle.smith.phd@gmail.com.
Focia PJ; Department of Biochemistry & Molecular Genetics, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA.
Chakravarthy S; Biophysics Collaborative Access Team, Advanced Photon Source, Argonne National Laboratory, Bldg. 435B/Sector 18, 9700 S. Cass Avenue, Argonne, IL 60439, USA.
Landahl EC; Department of Physics, DePaul University, Chicago, IL 60614, USA.
Klosowiak JL; Department of Cell & Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA.
Rice SE; Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Freymann DM; Department of Biochemistry & Molecular Genetics, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA. Electronic address: freymann@northwestern.edu.

J Struct Biol ; 212(3): 107656, 2020 12 01.

Article en En | MEDLINE | ID: mdl-33132189

Asunto(s)

GTP Fosfohidrolasas/química; GTP Fosfohidrolasas/metabolismo; Proteínas Mitocondriales/química; Proteínas Mitocondriales/metabolismo; Proteínas de Unión al GTP rho/química; Proteínas de Unión al GTP rho/metabolismo; Secuencia de Aminoácidos; Humanos; Mitocondrias/metabolismo; Membranas Mitocondriales/metabolismo; Dominios Proteicos/fisiología; Dispersión del Ángulo Pequeño; Difracción de Rayos X/métodos

Palabras clave

Crystal structure; GTP-binding protein; Gem1p; Miro; Mitochondrial dynamics; RhoT

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Unión al GTP rho / Proteínas Mitocondriales / GTP Fosfohidrolasas Límite: Humans Idioma: En Revista: J Struct Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

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