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The SGLT2 inhibitor Empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2/ROS/NLRP3/Caspase-1-dependent IL-1ß and IL-18 secretion.
Sukhanov, Sergiy; Higashi, Yusuke; Yoshida, Tadashi; Mummidi, Srinivas; Aroor, Annayya R; Jeffrey Russell, Jacob; Bender, Shawn B; DeMarco, Vincent G; Chandrasekar, Bysani.
Afiliación
  • Sukhanov S; Medicine, Tulane University School of Medicine, New Orleans, LA, USA. Electronic address: ssukhano@tulane.edu.
  • Higashi Y; Medicine, Tulane University School of Medicine, New Orleans, LA, USA. Electronic address: yhigashi@tulane.edu.
  • Yoshida T; Medicine, Tulane University School of Medicine, New Orleans, LA, USA. Electronic address: tyoshida@tulane.edu.
  • Mummidi S; Department of Human Genetics, South Texas Diabetes and Obesity Institute, The University of Texas Rio Grande Valley School of Medicine, Edinburg, TX, USA. Electronic address: srinivas.mummidi@utrgv.edu.
  • Aroor AR; Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO, USA; Department of Medicine, University of Missouri School of Medicine, Columbia, MO, USA. Electronic address: aroora@missouri.edu.
  • Jeffrey Russell J; Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO, USA; Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA. Electronic address: jjr99d@mail.missouri.edu.
  • Bender SB; Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO, USA; Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA; Dalton Cardiovascular Center, University of Missouri, Columbia, MO, USA. Electronic address: benders@missouri.edu.
  • DeMarco VG; Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO, USA; Department of Medicine, University of Missouri School of Medicine, Columbia, MO, USA; Dalton Cardiovascular Center, University of Missouri, Columbia, MO, USA; Medical Pharmacology and Physiology, University of Missouri,
  • Chandrasekar B; Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO, USA; Department of Medicine, University of Missouri School of Medicine, Columbia, MO, USA; Dalton Cardiovascular Center, University of Missouri, Columbia, MO, USA; Medical Pharmacology and Physiology, University of Missouri,
Cell Signal ; 77: 109825, 2021 01.
Article en En | MEDLINE | ID: mdl-33160017
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Bencidrilo / ARN / Caspasa 1 / Interleucina-18 / Proliferación Celular / Interleucina-1beta / Inhibidores del Cotransportador de Sodio-Glucosa 2 / Glucósidos Límite: Humans Idioma: En Revista: Cell Signal Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Bencidrilo / ARN / Caspasa 1 / Interleucina-18 / Proliferación Celular / Interleucina-1beta / Inhibidores del Cotransportador de Sodio-Glucosa 2 / Glucósidos Límite: Humans Idioma: En Revista: Cell Signal Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido