LncRNA STXBP5-AS1 suppresses stem cell-like properties of pancreatic cancer by epigenetically inhibiting neighboring androglobin gene expression.

Chen, Shi; Huang, Long; Li, Ge; Qiu, Funan; Wang, Yaodong; Yang, Can; Pan, Jingjing; Wu, Zhangwei; Chen, Jiangzhi; Tian, Yifeng

Chen, Shi; Huang, Long; Li, Ge; Qiu, Funan; Wang, Yaodong; Yang, Can; Pan, Jingjing; Wu, Zhangwei; Chen, Jiangzhi; Tian, Yifeng.

Afiliación

Chen S; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, No. 134 East Street, Fuzhou, 350001, Fujian, China. wawljwalj@126.com.
Huang L; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, No. 134 East Street, Fuzhou, 350001, Fujian, China.
Li G; Department of Hepatobiliary Surgery, Union Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.
Qiu F; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, No. 134 East Street, Fuzhou, 350001, Fujian, China.
Wang Y; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, No. 134 East Street, Fuzhou, 350001, Fujian, China.
Yang C; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, No. 134 East Street, Fuzhou, 350001, Fujian, China.
Pan J; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, No. 134 East Street, Fuzhou, 350001, Fujian, China.
Wu Z; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, No. 134 East Street, Fuzhou, 350001, Fujian, China.
Chen J; Department of Hepatobiliary Surgery, Union Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China. zeysson1@126.com.
Tian Y; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, No. 134 East Street, Fuzhou, 350001, Fujian, China. tianyifengsl@126.com.

Clin Epigenetics ; 12(1): 168, 2020 11 07.

Article en En | MEDLINE | ID: mdl-33160411

Asunto(s)

Proteínas Adaptadoras del Transporte Vesicular/genética; Proteínas de Unión a Calmodulina/genética; Carcinoma de Pulmón de Células no Pequeñas/genética; Globinas/genética; Neoplasias Pancreáticas/genética; ARN Largo no Codificante/genética; Proteínas Adaptadoras del Transporte Vesicular/farmacología; Animales; Anexina A5/metabolismo; Apoptosis/genética; Proteínas de Unión a Calmodulina/efectos de los fármacos; Caspasa 3/metabolismo; Proliferación Celular/efectos de los fármacos; Metilación de ADN; Proteína Potenciadora del Homólogo Zeste 2/genética; Epigenómica; Regulación Neoplásica de la Expresión Génica; Globinas/efectos de los fármacos; Humanos; Neoplasias Pulmonares/secundario; Ratones; Modelos Animales; Neoplasias Pancreáticas/patología; Células Madre/efectos de los fármacos; Células Madre/metabolismo; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

ADGB; Long non-coding RNA; Pancreatic cancer; STXBP5-AS1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteínas de Unión a Calmodulina / Globinas / Carcinoma de Pulmón de Células no Pequeñas / Proteínas Adaptadoras del Transporte Vesicular / ARN Largo no Codificante Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Clin Epigenetics Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania

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