Testis-Preserving Tumor Enucleation Is Applicable in Children with Immature Testicular Teratoma.
Urol Int
; 105(1-2): 27-30, 2021.
Article
en En
| MEDLINE
| ID: mdl-33176305
ABSTRACT
INTRODUCTION:
This study investigated the biological characteristics of immature testicular teratoma in children and explored the feasibility of testis-preserving tumor enucleation.METHODS:
We retrospectively reviewed the cases of 23 children who received a pathologic diagnosis of immature testicular teratoma between January 2005 and December 2018. Ages ranged from 16 days to 13 months (mean 6 months and 5 days). Painless testicular enlargement was the main clinical manifestation, and the course of disease ranged from 20 days to 4 months (mean 1.4 months). The tumor volume ranged from 1.5 × 1.2 × 0.5 to 6 × 5 × 4.5 cm. Elevated levels of alpha-fetoprotein were measured in 21 patients. Preoperative ultrasound examination showed a cystic/solid mass with calcification.RESULTS:
Excision of the affected testis was done in 10 patients and testis-preserving tumor excision in 13 patients. Postoperative chemotherapy was not employed. Nineteen patients were followed up for 1-10 years, and all showed disease-free survival without recurrence or metastasis.CONCLUSION:
Immature testicular teratoma is found predominantly in children aged <1 year, and its biological characteristics are different from those in adults. Immature testicular teratoma is largely benign in children and can be managed by testis-preserving tumor enucleation, as for other benign tumors (such as mature teratoma). Postoperative monitoring and follow-up are necessary.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Teratoma
/
Neoplasias Testiculares
/
Orquiectomía
/
Tratamientos Conservadores del Órgano
Tipo de estudio:
Observational_studies
Límite:
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
Urol Int
Año:
2021
Tipo del documento:
Article
País de afiliación:
China