pH-Dependent peptide bond formation by the selective coupling of α-amino acids in water.
Chem Commun (Camb)
; 57(1): 73-76, 2021 Jan 05.
Article
en En
| MEDLINE
| ID: mdl-33242043
ABSTRACT
A novel mechanism enabling selective peptide elongation by coupling α-amino acids over other potentially competing prebiotic amines under acidic aqueous condition is suggested. It proceeds via the generation of a carboxylic acid anhydride intermediate with subsequent intramolecular formation of the amide bond.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Péptidos
/
Aminoácidos
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2021
Tipo del documento:
Article