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Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Jutzi, Daniel; Campagne, Sébastien; Schmidt, Ralf; Reber, Stefan; Mechtersheimer, Jonas; Gypas, Foivos; Schweingruber, Christoph; Colombo, Martino; von Schroetter, Christine; Loughlin, Fionna E; Devoy, Anny; Hedlund, Eva; Zavolan, Mihaela; Allain, Frédéric H-T; Ruepp, Marc-David.
Afiliación
  • Jutzi D; United Kingdom Dementia Research Institute Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • Campagne S; Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zürich, CH-8093, Zürich, Switzerland.
  • Schmidt R; Computational and Systems Biology, Biozentrum, University of Basel, CH-4056, Basel, Switzerland.
  • Reber S; United Kingdom Dementia Research Institute Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • Mechtersheimer J; United Kingdom Dementia Research Institute Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • Gypas F; Computational and Systems Biology, Biozentrum, University of Basel, CH-4056, Basel, Switzerland.
  • Schweingruber C; Friedrich Miescher Institute for Biomedical Research, CH-4058, Basel, Switzerland.
  • Colombo M; Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
  • von Schroetter C; Celgene Institute of Translational Research (CITRE), 41092, Seville, Spain.
  • Loughlin FE; Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zürich, CH-8093, Zürich, Switzerland.
  • Devoy A; Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zürich, CH-8093, Zürich, Switzerland.
  • Hedlund E; Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, 3800, Australia.
  • Zavolan M; United Kingdom Dementia Research Institute Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • Allain FH; Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
  • Ruepp MD; Computational and Systems Biology, Biozentrum, University of Basel, CH-4056, Basel, Switzerland.
Nat Commun ; 11(1): 6341, 2020 12 11.
Article en En | MEDLINE | ID: mdl-33311468
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Nuclear Pequeño / Ribonucleoproteína Nuclear Pequeña U1 / Proteína FUS de Unión a ARN / Esclerosis Amiotrófica Lateral Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Nuclear Pequeño / Ribonucleoproteína Nuclear Pequeña U1 / Proteína FUS de Unión a ARN / Esclerosis Amiotrófica Lateral Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido