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CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies.
Wang, Dongrui; Prager, Briana C; Gimple, Ryan C; Aguilar, Brenda; Alizadeh, Darya; Tang, Hongzhen; Lv, Deguan; Starr, Renate; Brito, Alfonso; Wu, Qiulian; Kim, Leo J Y; Qiu, Zhixin; Lin, Peng; Lorenzini, Michael H; Badie, Behnam; Forman, Stephen J; Xie, Qi; Brown, Christine E; Rich, Jeremy N.
Afiliación
  • Wang D; T Cell Therapeutics Research Labs, Cellular Immunotherapy Center, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California.
  • Prager BC; Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, San Diego, California.
  • Gimple RC; Cleveland Clinic Lerner College of Medicine at Cleveland Clinic and Case Western Reserve University, Cleveland, Ohio.
  • Aguilar B; Sanford Consortium for Regenerative Medicine, La Jolla, California.
  • Alizadeh D; Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, San Diego, California.
  • Tang H; Sanford Consortium for Regenerative Medicine, La Jolla, California.
  • Lv D; Department of Pathology, Case Western Reserve University, Cleveland, Ohio.
  • Starr R; T Cell Therapeutics Research Labs, Cellular Immunotherapy Center, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California.
  • Brito A; T Cell Therapeutics Research Labs, Cellular Immunotherapy Center, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California.
  • Wu Q; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
  • Kim LJY; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
  • Qiu Z; Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, Zhejiang Province, China.
  • Lin P; Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, San Diego, California.
  • Lorenzini MH; Sanford Consortium for Regenerative Medicine, La Jolla, California.
  • Badie B; T Cell Therapeutics Research Labs, Cellular Immunotherapy Center, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California.
  • Forman SJ; T Cell Therapeutics Research Labs, Cellular Immunotherapy Center, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California.
  • Xie Q; Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, San Diego, California.
  • Brown CE; Sanford Consortium for Regenerative Medicine, La Jolla, California.
  • Rich JN; Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, San Diego, California.
Cancer Discov ; 11(5): 1192-1211, 2021 05.
Article en En | MEDLINE | ID: mdl-33328215
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias Encefálicas / Glioblastoma / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Receptores Quiméricos de Antígenos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Cancer Discov Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias Encefálicas / Glioblastoma / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Receptores Quiméricos de Antígenos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Cancer Discov Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos