Drug-induced cutaneous vasculitis and anticoagulant-related cutaneous adverse reactions: insights in pathogenesis, clinical presentation, and treatment.
Clin Dermatol
; 38(6): 613-628, 2020.
Article
en En
| MEDLINE
| ID: mdl-33341196
ABSTRACT
Drug-induced vasculitis and anticoagulant-related skin reactions are commonly encountered in the inpatient and outpatient settings. The spectrum of clinical presentation is broad and ranges from focal, skin-limited disease, to more extensive cutaneous and soft tissue necrosis, to potentially fatal systemic involvement. The prompt recognition of these adverse events can have a significant impact on patient morbidity and mortality. We highlight the key features of the clinical presentation with an emphasis on primary lesion morphology, distribution, and epidemiology of purpuric drug reactions. The proposed pathophysiology, histologic findings, and therapeutic interventions of these potentially life-threatening diseases are discussed.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Púrpura
/
Vasculitis
/
Enfermedades Cutáneas Vasculares
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Clin Dermatol
Año:
2020
Tipo del documento:
Article