The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-&#954;B activation.

Mohanty, Suchitra; Han, Teng; Choi, Young Bong; Lavorgna, Alfonso; Zhang, Jiawen; Harhaj, Edward William

The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation.

Mohanty, Suchitra; Han, Teng; Choi, Young Bong; Lavorgna, Alfonso; Zhang, Jiawen; Harhaj, Edward William.

Afiliación

Mohanty S; Department of Microbiology and Immunology, Penn State College School of Medicine, Hershey, Pennsylvania, United States of America.
Han T; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Choi YB; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Lavorgna A; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Zhang J; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Harhaj EW; Department of Microbiology and Immunology, Penn State College School of Medicine, Hershey, Pennsylvania, United States of America.

PLoS Pathog ; 16(12): e1008504, 2020 12.

Article en En | MEDLINE | ID: mdl-33362245

Asunto(s)

Productos del Gen tax/metabolismo; FN-kappa B/metabolismo; Ubiquitina-Proteína Ligasas/metabolismo; Regulación de la Expresión Génica/genética; Genes pX/fisiología; Células HEK293; Virus Linfotrópico T Tipo 1 Humano/metabolismo; Virus Linfotrópico T Tipo 1 Humano/patogenicidad; Humanos; FN-kappa B/fisiología; Transducción de Señal/fisiología; Linfocitos T/metabolismo; Ubiquitina-Proteína Ligasas/fisiología; Ubiquitinación; Ubiquitinas/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos del Gen tax / FN-kappa B / Ubiquitina-Proteína Ligasas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: PLoS Pathog Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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