A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids.

Zanotelli, Vito Rt; Leutenegger, Matthias; Lun, Xiao-Kang; Georgi, Fanny; de Souza, Natalie; Bodenmiller, Bernd

Zanotelli, Vito Rt; Leutenegger, Matthias; Lun, Xiao-Kang; Georgi, Fanny; de Souza, Natalie; Bodenmiller, Bernd.

Afiliación

Zanotelli VR; Department of Quantitative Biomedicine, University of Zurich, Zürich, Switzerland.
Leutenegger M; Life Science Zürich Graduate School, ETH Zürich and University of Zürich, Zürich, Switzerland.
Lun XK; Department of Molecular Life Sciences, University of Zurich, Zürich, Switzerland.
Georgi F; Life Science Zürich Graduate School, ETH Zürich and University of Zürich, Zürich, Switzerland.
de Souza N; Department of Molecular Life Sciences, University of Zurich, Zürich, Switzerland.
Bodenmiller B; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.

Mol Syst Biol ; 16(12): e9798, 2020 12.

Article en En | MEDLINE | ID: mdl-33369114

Asunto(s)

Microambiente Celular; Imagenología Tridimensional; Esferoides Celulares/citología; Biomarcadores/metabolismo; Células Cultivadas; Humanos; Modelos Lineales; Fenotipo

Palabras clave

high-throughput assay; multiplexed imaging; spatial signaling; spatial variance; tissue organization

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esferoides Celulares / Imagenología Tridimensional / Microambiente Celular Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Syst Biol Asunto de la revista: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Suiza

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