The biological characteristics of the canine adenovirus type 1 from fox and the transcriptome analysis of the infected MDCK cell.
Cell Biol Int
; 45(5): 936-947, 2021 May.
Article
en En
| MEDLINE
| ID: mdl-33382191
ABSTRACT
Canine adenovirus type 1 (CAdV-1) is the etiologic agent of fox encephalitis, and a virus strain from fox encephalitis is isolated and related research are conducted. In this experiment, the results showed that the F1301 strain was confirmed to be the CAdV-1. The whole genome of the CAdV-1 F1301 strain isolated from fox was 30,535 bp and had higher homology to the other reported CAdV-1 strains. After 0, 12, and 36 h of CAdV-1 infection, the difference gene of the 592 long noncoding RNA and 11,215 microRNA were involved in cell responses to CAdV-1 infection through the PI3K-AKT, Wnt, Herpes simplex, hepatitis C, and Epstein-Barr virus infection pathway in Madin-Darby canine kidney cell line (MDCK). The results indicate that the biological characterization of the CAdV-1 and the MDCK cell-CAdV-1 interaction are clarified.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Adenovirus Caninos
/
Zorros
Límite:
Animals
Idioma:
En
Revista:
Cell Biol Int
Año:
2021
Tipo del documento:
Article
País de afiliación:
China