Fine-Tuning Multi-Gene Clusters via Well-Characterized Gene Expression Regulatory Elements: Case Study of the Arginine Synthesis Pathway in <i>C. glutamicum</i>.

Duan, Yanting; Zhai, Weiji; Liu, Weijia; Zhang, Xiaomei; Shi, Jin-Song; Zhang, Xiaojuan; Xu, Zhenghong

Fine-Tuning Multi-Gene Clusters via Well-Characterized Gene Expression Regulatory Elements: Case Study of the Arginine Synthesis Pathway in C. glutamicum.

Duan, Yanting; Zhai, Weiji; Liu, Weijia; Zhang, Xiaomei; Shi, Jin-Song; Zhang, Xiaojuan; Xu, Zhenghong.

Afiliación

Duan Y; National Engineering Laboratory for Cereal Fermentation Technology, Key Laboratory of Industrial Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
Zhai W; Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
Liu W; National Engineering Laboratory for Cereal Fermentation Technology, Key Laboratory of Industrial Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
Zhang X; Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
Shi JS; Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
Zhang X; School of Pharmaceutical Science, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
Xu Z; Jiangsu Engineering Research Center for Bioactive Products Processing Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.

ACS Synth Biol ; 10(1): 38-48, 2021 01 15.

Article en En | MEDLINE | ID: mdl-33382575

Asunto(s)

Arginina/biosíntesis; Corynebacterium glutamicum/metabolismo; Regulación Bacteriana de la Expresión Génica/genética; Sitios de Unión; Reactores Biológicos; Citrulina/biosíntesis; ARN Polimerasas Dirigidas por ADN/metabolismo; Ingeniería Metabólica; Familia de Multigenes/genética; Regiones Promotoras Genéticas; Ribosomas/metabolismo

Palabras clave

Corynebacterium glutamicum; RBS; arginine synthesis pathway; combination effects; orthogonality; promoter

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arginina / Regulación Bacteriana de la Expresión Génica / Corynebacterium glutamicum Idioma: En Revista: ACS Synth Biol Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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