Deletion of P21-activated kinase-1 induces age-dependent increased visceral adiposity and cardiac dysfunction in female mice.

Batra, Ashley; Warren, Chad M; Ke, Yunbo; McCann, Maximilian; Halas, Monika; Capote, Andrielle E; Liew, Chong Wee; Solaro, R John; Rosas, Paola C

Batra, Ashley; Warren, Chad M; Ke, Yunbo; McCann, Maximilian; Halas, Monika; Capote, Andrielle E; Liew, Chong Wee; Solaro, R John; Rosas, Paola C.

Afiliación

Batra A; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA.
Warren CM; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA.
Ke Y; Department of Anesthesiology, School of Medicine, University of Maryland, Baltimore, MD, USA.
McCann M; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA.
Halas M; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA.
Capote AE; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA.
Liew CW; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA.
Solaro RJ; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA.
Rosas PC; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA. prosas@uic.edu.

Mol Cell Biochem ; 476(3): 1337-1349, 2021 Mar.

Article en En | MEDLINE | ID: mdl-33389497

Asunto(s)

Adiposidad; Grasa Intraabdominal/metabolismo; Disfunción Ventricular/metabolismo; Quinasas p21 Activadas/genética; Quinasas p21 Activadas/metabolismo; Envejecimiento; Animales; Diástole; Ecocardiografía; Femenino; Corazón/fisiología; Insuficiencia Cardíaca/metabolismo; Masculino; Ratones; Ratones Noqueados; Miocardio/metabolismo; Fosforilación; Volumen Sistólico; Proteína de Unión al GTP cdc42/metabolismo

Palabras clave

Adipose tissue; Aging; Diastolic dysfunction; Females; Heart failure with preserved ejection fraction; Obesity; P21-activated kinase-1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Disfunción Ventricular / Grasa Intraabdominal / Adiposidad / Quinasas p21 Activadas Límite: Animals Idioma: En Revista: Mol Cell Biochem Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos

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