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Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis.
Mehta, Arpan R; Gregory, Jenna M; Dando, Owen; Carter, Roderick N; Burr, Karen; Nanda, Jyoti; Story, David; McDade, Karina; Smith, Colin; Morton, Nicholas M; Mahad, Don J; Hardingham, Giles E; Chandran, Siddharthan; Selvaraj, Bhuvaneish T.
Afiliación
  • Mehta AR; UK Dementia Research Institute at University of Edinburgh, University of Edinburgh, Edinburgh bioQuarter, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.
  • Gregory JM; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Dando O; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK.
  • Carter RN; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, UK.
  • Burr K; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
  • Nanda J; UK Dementia Research Institute at University of Edinburgh, University of Edinburgh, Edinburgh bioQuarter, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.
  • Story D; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • McDade K; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, UK.
  • Smith C; MRC Edinburgh Brain Bank, Academic Department of Neuropathology, University of Edinburgh, Edinburgh, UK.
  • Morton NM; Edinburgh Pathology, University of Edinburgh, Edinburgh, UK.
  • Mahad DJ; UK Dementia Research Institute at University of Edinburgh, University of Edinburgh, Edinburgh bioQuarter, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.
  • Hardingham GE; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Chandran S; University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
  • Selvaraj BT; UK Dementia Research Institute at University of Edinburgh, University of Edinburgh, Edinburgh bioQuarter, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.
Acta Neuropathol ; 141(2): 257-279, 2021 02.
Article en En | MEDLINE | ID: mdl-33398403
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Axones / Metabolismo Energético / Proteína C9orf72 / Esclerosis Amiotrófica Lateral / Mitocondrias / Neuronas Motoras Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neuropathol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Axones / Metabolismo Energético / Proteína C9orf72 / Esclerosis Amiotrófica Lateral / Mitocondrias / Neuronas Motoras Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neuropathol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Alemania