Detection and Analysis of Ceramide in Skin and Blood in a Healthy Chinese Population.
J Cosmet Sci
; 71(6): 367-375, 2020.
Article
en En
| MEDLINE
| ID: mdl-33413781
ABSTRACT
To explore the significance of ceramide in the skin barrier and its potential utility within the cosmetics industry, an accurate and high-speed method was used to detect the types of ceramides in the skin and blood of a healthy Chinese population. Forearm cortical skin stratum corneum samples were obtained from four healthy subjects using a noninvasive method. In addition, these subjects were collected intravenously to obtain blood samples. Ceramides were detected in skin and blood samples using high-performance liquid chromatography coupled with specialized high-resolution Fourier Transform mass spectrometry machine. Data were analyzed using full-flow lipid analysis software. Peaks representing ceramides were detected in all skin samples and some blood samples. The results show that ceramides in skin are predominantly long-chain ceramides, but mainly short-chain in the blood. Simple and fast qualitative and quantitative analysis of ceramide in the skin and blood provides a basis for the precise addition of ceramide in future skin care products and the metabolic regulation and prevention of various diseases.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piel
/
Ceramidas
Tipo de estudio:
Diagnostic_studies
/
Qualitative_research
Límite:
Humans
Idioma:
En
Revista:
J Cosmet Sci
Asunto de la revista:
QUIMICA CLINICA
Año:
2020
Tipo del documento:
Article