Topical treatment of vulvodynia, dyspareunia and pudendal neuralgia: A single clinic audit of amitriptyline and oestriol in organogel.
Aust N Z J Obstet Gynaecol
; 61(2): 270-274, 2021 04.
Article
en En
| MEDLINE
| ID: mdl-33427301
ABSTRACT
BACKGROUND:
Vulvodynia and pudendal neuralgia comprise significant contributors to vulvar-related pain and its impact on daily life.AIM:
A retrospective clinical audit was conducted at the Women's Health & Research Institute of Australia, Sydney, to determine the pattern of use and the efficacy of the application of topical amitriptyline 0.5% plus oestriol 0.03% in organogel (AOO), to the vulvar vestibule in reducing the impact of pain on daily life. MATERIALS ANDMETHODS:
There were 1174 patients who received a script from May 2017 until February 2020 1054 patients agreed to be contacted and had a valid email address.RESULTS:
There were 376 (35.7%) patients who replied. Pain with intercourse was the main indication for use. Treatment was rated effective by 51.2% (95% CI 35.4-66.8%) of patients less than 30 years of age, 66.7% (95% CI 57.3-74.9%) of patients 30-50 years of age, and 58.3% (95% CI 50.9-65.4%) in patients over 50. Stinging at the site of application was the most commonly reported side effect.CONCLUSION:
Topical AOO is an effective and well-tolerated treatment for vulvar pain.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dispareunia
/
Vulvodinia
/
Neuralgia del Pudendo
Tipo de estudio:
Observational_studies
Límite:
Aged
/
Female
/
Humans
/
Middle aged
País/Región como asunto:
Oceania
Idioma:
En
Revista:
Aust N Z J Obstet Gynaecol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Australia