Insights in the structural understanding of amyloidogenicity and mutation-led conformational dynamics of amyloid beta (Aß) through molecular dynamics simulations and principal component analysis.

Raghavan, Sriram Srinivasa; Iqbal, Saleem; Ayyadurai, Niraikulam; Gunasekaran, Krishnasamy

Raghavan, Sriram Srinivasa; Iqbal, Saleem; Ayyadurai, Niraikulam; Gunasekaran, Krishnasamy.

Afiliación

Raghavan SS; Department of Crystallography and Biophysics, University of Madras, Chennai, India.
Iqbal S; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Ayyadurai N; Division of Biotechnology, Council of Scientific and Industrial Research-Central Leather Research Institute (CSIR-CLRI), Chennai, India.
Gunasekaran K; Department of Crystallography and Biophysics, University of Madras, Chennai, India.

J Biomol Struct Dyn ; 40(12): 5577-5587, 2022 08.

Article en En | MEDLINE | ID: mdl-33438527

Asunto(s)

Enfermedad de Alzheimer; Péptidos beta-Amiloides; Enfermedad de Alzheimer/metabolismo; Péptidos beta-Amiloides/química; Humanos; Simulación de Dinámica Molecular; Mutación; Fragmentos de Péptidos/química; Análisis de Componente Principal

Palabras clave

Alzheimer's disease; Amyloid ß (Aß); dynamic residual correlation; mutational analysis; principal component analysis

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos beta-Amiloides / Enfermedad de Alzheimer Límite: Humans Idioma: En Revista: J Biomol Struct Dyn Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google