Veno-occlusive disease of the liver in captive cheetah.
Vet Pathol
; 25(1): 48-57, 1988 Jan.
Article
en En
| MEDLINE
| ID: mdl-3344570
ABSTRACT
Liver tissues from 126 captive cheetah were evaluated by light microscopy and histochemistry; eight animals were evaluated by electron microscopy. The main hepatic lesion, a vascular lesion resembling veno-occlusive disease (VOD) of the liver and characterized by subendothelial fibrosis and proliferation of smooth muscle-like cells in the central veins, was seen in 60% of the sexually mature cheetah. Although this hepatic vascular lesion was seen in cheetah as young as 1 year of age, the most severe lesions, usually associated with liver failure, were found in cheetah between the ages of 6 and 11. There was no sex predisposition, and in approximately 40% of the VOD cases, liver disease was not suspected clinically or at necropsy. VOD was found in other felidae, especially in the snow leopard. High levels of vitamin A in livers, as well as in diets of the cheetah, could be a contributing factor in the development of VOD in some groups of cheetah.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad Veno-Oclusiva Hepática
/
Carnívoros
/
Acinonyx
/
Hígado
Límite:
Animals
Idioma:
En
Revista:
Vet Pathol
Año:
1988
Tipo del documento:
Article