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A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation.
Lo, Yuan-Hung; Kolahi, Kevin S; Du, Yuhong; Chang, Chiung-Ying; Krokhotin, Andrey; Nair, Ajay; Sobba, Walter D; Karlsson, Kasper; Jones, Sunny J; Longacre, Teri A; Mah, Amanda T; Tercan, Bahar; Sockell, Alexandra; Xu, Hang; Seoane, Jose A; Chen, Jin; Shmulevich, Ilya; Weissman, Jonathan S; Curtis, Christina; Califano, Andrea; Fu, Haian; Crabtree, Gerald R; Kuo, Calvin J.
Afiliación
  • Lo YH; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California.
  • Kolahi KS; Department of Pathology, Stanford University School of Medicine, Stanford, California.
  • Du Y; Department of Pharmacology and Chemical Biology and Emory Chemical Biology Discovery Center, Emory University School of Medicine, Atlanta, Georgia.
  • Chang CY; Department of Pathology, Stanford University School of Medicine, Stanford, California.
  • Krokhotin A; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California.
  • Nair A; Department of Systems Biology, Columbia University, New York, New York.
  • Sobba WD; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California.
  • Karlsson K; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California.
  • Jones SJ; Division of Oncology, Stanford University School of Medicine, Stanford, California.
  • Longacre TA; Department of Systems Biology, Columbia University, New York, New York.
  • Mah AT; Department of Pathology, Stanford University School of Medicine, Stanford, California.
  • Tercan B; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California.
  • Sockell A; Institute for Systems Biology, Seattle, Washington.
  • Xu H; Division of Oncology, Stanford University School of Medicine, Stanford, California.
  • Seoane JA; Division of Oncology, Stanford University School of Medicine, Stanford, California.
  • Chen J; Division of Oncology, Stanford University School of Medicine, Stanford, California.
  • Shmulevich I; Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California.
  • Weissman JS; Department of Pharmacology and Cecil H. and Ida Green Center for Reproductive Biology Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
  • Curtis C; Institute for Systems Biology, Seattle, Washington.
  • Califano A; Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California.
  • Fu H; Division of Oncology, Stanford University School of Medicine, Stanford, California.
  • Crabtree GR; Department of Systems Biology, Columbia University, New York, New York.
  • Kuo CJ; Department of Pharmacology and Chemical Biology and Emory Chemical Biology Discovery Center, Emory University School of Medicine, Atlanta, Georgia.
Cancer Discov ; 11(6): 1562-1581, 2021 06.
Article en En | MEDLINE | ID: mdl-33451982
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Factores de Transcripción / Transformación Celular Neoplásica / Proteínas de Unión al ADN / Sistemas CRISPR-Cas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Discov Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Factores de Transcripción / Transformación Celular Neoplásica / Proteínas de Unión al ADN / Sistemas CRISPR-Cas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Discov Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos