[The application progress of fluid de-escalation therapy in abdominal infection-induced septic shock].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
; 32(11): 1403-1408, 2020 Nov.
Article
en Zh
| MEDLINE
| ID: mdl-33463507
ABSTRACT
After adequate fluid resuscitation in the early stage of septic shock, excessive accumulation of fluid in the body leads to organ dysfunction, which prolongs hospitalization, mechanical ventilation time, and renal replacement therapy time, and is associated with poor prognosis. The fluid de-escalation therapy is an important fluid management strategy performed in the late stage of septic shock. It aims to clear excess fluid by restricting fluid infusion, using diuretics and renal replacement therapy to achieve a negative fluid balance. The fluid de-escalation therapy contributes to improve clinical outcome of septic shock patients and reduce the mortality. This review mainly discusses the current researches and application progress of the fluid de-escalation therapy of abdominal infection-induced septic shock through clarifying its origin, time and endpoint, method of the therapy, the relationship with the control of the source of abdominal infection and its impact on organ function and clinical outcome. Our study intends to provide guidance for the treatment of abdominal infection-induced septic shock in the late stage, and explore the novel research directions.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Choque Séptico
/
Infecciones Intraabdominales
Tipo de estudio:
Guideline
Límite:
Humans
Idioma:
Zh
Revista:
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Año:
2020
Tipo del documento:
Article
País de afiliación:
China