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p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).
Maor-Nof, Maya; Shipony, Zohar; Lopez-Gonzalez, Rodrigo; Nakayama, Lisa; Zhang, Yong-Jie; Couthouis, Julien; Blum, Jacob A; Castruita, Patricia A; Linares, Gabriel R; Ruan, Kai; Ramaswami, Gokul; Simon, David J; Nof, Aviv; Santana, Manuel; Han, Kyuho; Sinnott-Armstrong, Nasa; Bassik, Michael C; Geschwind, Daniel H; Tessier-Lavigne, Marc; Attardi, Laura D; Lloyd, Thomas E; Ichida, Justin K; Gao, Fen-Biao; Greenleaf, William J; Yokoyama, Jennifer S; Petrucelli, Leonard; Gitler, Aaron D.
Afiliación
  • Maor-Nof M; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: maormaya@stanford.edu.
  • Shipony Z; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Lopez-Gonzalez R; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Nakayama L; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Zhang YJ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Couthouis J; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Blum JA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Castruita PA; Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
  • Linares GR; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA.
  • Ruan K; Department of Neurology, Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
  • Ramaswami G; Department of Neurology, Program in Neurogenetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Simon DJ; Department of Biology, Stanford University, Stanford, CA, USA.
  • Nof A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Santana M; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA.
  • Han K; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Sinnott-Armstrong N; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Geschwind DH; Department of Neurology, Program in Neurogenetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Tessier-Lavigne M; Department of Biology, Stanford University, Stanford, CA, USA.
  • Attardi LD; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
  • Lloyd TE; Department of Neurology, Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
  • Ichida JK; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA.
  • Gao FB; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Greenleaf WJ; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Yokoyama JS; Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
  • Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Gitler AD; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: agitler@stanford.edu.
Cell ; 184(3): 689-708.e20, 2021 02 04.
Article en En | MEDLINE | ID: mdl-33482083

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Expansión de las Repeticiones de ADN / Proteína C9orf72 / Degeneración Nerviosa Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Expansión de las Repeticiones de ADN / Proteína C9orf72 / Degeneración Nerviosa Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article