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Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis.
Watson, Avia; Li, Hao; Ma, Bingting; Weiss, Ronen; Bendayan, Daniele; Abramovitz, Lilach; Ben-Shalom, Noam; Mor, Michael; Pinko, Erica; Bar Oz, Michal; Wang, Zhenqi; Du, Fengjiao; Lu, Yu; Rybniker, Jan; Dahan, Rony; Huang, Hairong; Barkan, Daniel; Xiang, Ye; Javid, Babak; Freund, Natalia T.
Afiliación
  • Watson A; Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
  • Li H; Centre for Global Health and Infectious Diseases, Collaborative Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, Tsinghua University School of Medicine, Beijing, China.
  • Ma B; College of Veterinary Medicine, China Agricultural University, Beijing, China.
  • Weiss R; Advanced Innovation Center for Structural Biology & Beijing Frontier Research Center for Biological Structure, Tsinghua University School of Medicine, Beijing, China.
  • Bendayan D; Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
  • Abramovitz L; Pulmonary and Tuberculosis Department, Shmuel Harofe Hospital, Be'er Ya'akov, Israel.
  • Ben-Shalom N; Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
  • Mor M; Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
  • Pinko E; Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
  • Bar Oz M; Pulmonary and Tuberculosis Department, Shmuel Harofe Hospital, Be'er Ya'akov, Israel.
  • Wang Z; Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
  • Du F; Centre for Global Health and Infectious Diseases, Collaborative Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, Tsinghua University School of Medicine, Beijing, China.
  • Lu Y; Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing, China.
  • Rybniker J; Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing, China.
  • Dahan R; Department of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany.
  • Huang H; German Center for Infection Research (DZIF), Bonn-Cologne, Germany.
  • Barkan D; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Xiang Y; National Clinical Laboratory on Tuberculosis, Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing, China.
  • Javid B; Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
  • Freund NT; Advanced Innovation Center for Structural Biology & Beijing Frontier Research Center for Biological Structure, Tsinghua University School of Medicine, Beijing, China. yxiang@mail.tsinghua.edu.cn.
Nat Commun ; 12(1): 602, 2021 01 27.
Article en En | MEDLINE | ID: mdl-33504803

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Transporte de Membrana / Proteínas Bacterianas / Tuberculosis / Anticuerpos Antibacterianos / Mycobacterium tuberculosis Límite: Adult / Animals / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Transporte de Membrana / Proteínas Bacterianas / Tuberculosis / Anticuerpos Antibacterianos / Mycobacterium tuberculosis Límite: Adult / Animals / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Reino Unido