[Thyrotoxic hypokalemic periodic paralysis in two African black women]. / Paralysie périodique hypokaliémique thyrotoxique chez deux femmes noires africaines.
Pan Afr Med J
; 37: 207, 2020.
Article
en Fr
| MEDLINE
| ID: mdl-33505575
ABSTRACT
Thyrotoxic hypokalemic periodic paralysis is a rare complication of hyperthyroidism. It has been most often reported in Asian subjects while it has been little described in the black population. Its mechanism has been little elucidated, but it would be caused by hyperactivity of the Na+/K+pump. We here report two cases of thyrotoxic hypokalemic periodic paralysis in black African subjects. The clinical manifestation was identical in both patients proximal muscle paralysis of the lower limbs. Paralysis was associated with severe hypokalemia and occurred in female patients treated for Graves' disease without any other associated disease. Outcome was immediately favorable under potassium supplementation. Treatment of hyperthyroidism prevented recurrences. This study highlights the importance of suspecting the diagnosis of thyrotoxic hypokalemic periodic paralysis despite its rarity in the black African population.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tirotoxicosis
/
Enfermedad de Graves
/
Parálisis Periódica Hipopotasémica
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
Fr
Revista:
Pan Afr Med J
Año:
2020
Tipo del documento:
Article