Structure-Guided Computational Methods Predict Multiple Distinct Binding Modes for Pyrazoloquinolinones in GABA<sub>A</sub> Receptors.

Fabjan, Jure; Koniuszewski, Filip; Schaar, Benjamin; Ernst, Margot

Structure-Guided Computational Methods Predict Multiple Distinct Binding Modes for Pyrazoloquinolinones in GABA_A Receptors.

Fabjan, Jure; Koniuszewski, Filip; Schaar, Benjamin; Ernst, Margot.

Afiliación

Fabjan J; Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Vienna, Austria.
Koniuszewski F; Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Vienna, Austria.
Schaar B; Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Vienna, Austria.
Ernst M; Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Vienna, Austria.

Front Neurosci ; 14: 611953, 2020.

Article en En | MEDLINE | ID: mdl-33519364

Palabras clave

GABAA receptor; allosteric modulation; computational docking; functional selectivity; pharmacophore analysis; pyrazoloquinolinone

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Neurosci Año: 2020 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Suiza

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