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Isoform- and Phosphorylation-specific Multiplexed Quantitative Pharmacodynamics of Drugs Targeting PI3K and MAPK Signaling in Xenograft Models and Clinical Biopsies.
Herrick, William G; Kilpatrick, Casey L; Hollingshead, Melinda G; Esposito, Dominic; O'Sullivan Coyne, Geraldine; Gross, Andrea M; Johnson, Barry C; Chen, Alice P; Widemann, Brigitte C; Doroshow, James H; Parchment, Ralph E; Srivastava, Apurva K.
Afiliación
  • Herrick WG; Clinical Pharmacodynamics Biomarker Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland.
  • Kilpatrick CL; Clinical Pharmacodynamics Biomarker Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland.
  • Hollingshead MG; Biological Testing Branch, NCI, Frederick, Maryland.
  • Esposito D; Protein Expression Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland.
  • O'Sullivan Coyne G; Division of Cancer Treatment and Diagnosis, NCI, Bethesda, Maryland.
  • Gross AM; Pediatric Oncology Branch, NCI, Bethesda, Maryland.
  • Johnson BC; Center for Cancer Research, NCI, Bethesda, Maryland.
  • Chen AP; Division of Cancer Treatment and Diagnosis, NCI, Bethesda, Maryland.
  • Widemann BC; Division of Cancer Treatment and Diagnosis, NCI, Bethesda, Maryland.
  • Doroshow JH; Pediatric Oncology Branch, NCI, Bethesda, Maryland.
  • Parchment RE; Center for Cancer Research, NCI, Bethesda, Maryland.
  • Srivastava AK; Division of Cancer Treatment and Diagnosis, NCI, Bethesda, Maryland.
Mol Cancer Ther ; 20(4): 749-760, 2021 04.
Article en En | MEDLINE | ID: mdl-33536190
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Proteínas Quinasas Activadas por Mitógenos / Proteínas Proto-Oncogénicas c-akt Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Proteínas Quinasas Activadas por Mitógenos / Proteínas Proto-Oncogénicas c-akt Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos