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Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation.
Maciuszek, Monika; Ortega-Gomez, Almudena; Maas, Sanne L; Perretti, Mauro; Merritt, Andy; Soehnlein, Oliver; Chapman, Timothy M.
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  • Maciuszek M; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK; The William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK. Electronic address: maciuszekmonika@gmail.com.
  • Ortega-Gomez A; Institute for Cardiovascular Prevention (IPEK), LMU Munich Hospital, Munich, Germany.
  • Maas SL; Institute for Cardiovascular Prevention (IPEK), LMU Munich Hospital, Munich, Germany.
  • Perretti M; The William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.
  • Merritt A; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK.
  • Soehnlein O; Institute for Cardiovascular Prevention (IPEK), LMU Munich Hospital, Munich, Germany; Department of Physiology and Pharmacology (FyFa), Karolinska Institute, Stockholm, Sweden; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance (MHA), Munich, Germany.
  • Chapman TM; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK.
Eur J Med Chem ; 214: 113194, 2021 Mar 15.
Article en En | MEDLINE | ID: mdl-33548634
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Urea / Enfermedades Cardiovasculares / Antiinflamatorios no Esteroideos / Ciclopentanos / Receptores de Lipoxina / Receptores de Formil Péptido / Inflamación Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Urea / Enfermedades Cardiovasculares / Antiinflamatorios no Esteroideos / Ciclopentanos / Receptores de Lipoxina / Receptores de Formil Péptido / Inflamación Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article Pais de publicación: Francia