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[Sertraline-induced chronic eosinophilic pneumonia]. / Pneumopathie chronique à éosinophiles induite par la sertraline.
Brancaleone, P; Descamps, O; Piquet, M; Detry, G; Mignon, M; Weynand, B.
Afiliación
  • Brancaleone P; Service de pneumologie, centres hospitaliers Jolimont, 7100 La Louvière, Belgique. Electronic address: pierre.brancaleone@gmail.com.
  • Descamps O; Service de médecine interne, centres hospitaliers Jolimont, 7100 La Louvière, Belgique.
  • Piquet M; Service de pneumologie, centres hospitaliers Jolimont, 7100 La Louvière, Belgique.
  • Detry G; Laboratoire de biologie clinique, centres hospitaliers Jolimont, 7100 La Louvière, Belgique.
  • Mignon M; Service de radiologie, centres hospitaliers Jolimont, 7100 La Louvière, Belgique.
  • Weynand B; Service d'anatomopathologie, universitair ziekenhuis Leuven-Gasthuisberg, 3000 Leuven, Belgique.
Rev Mal Respir ; 38(2): 210-214, 2021 Feb.
Article en Fr | MEDLINE | ID: mdl-33581985
INTRODUCTION: Sertraline is a selective serotonin reuptake inhibitor which is often used as first-line treatment for depression. Several patterns of interstitial lung disease attributable to sertraline have been reported in the literature. CASE REPORT: A 69-year-old patient, who had been taking sertraline to treat severe depression for 10 months, presented with a deterioration in his general condition and respiratory symptoms found to be associated with bilateral pneumonitis. An exhaustive assessment did not reveal any infectious or autoimmune aetiology. Transthoracic lung biopsy revealed a pattern of eosinophilic lung disease. Sertraline-induced lung toxicity was then suspected and this treatment was therefore stopped. The patient's symptoms resolved and the chest imaging normalized. CONCLUSIONS: Our observation suggests that sertraline was the cause of chronic eosinophilic pneumonia characterized by an insidious clinical presentation several months after starting the medication. Given its widespread prescription, we encourage any clinician facing this disease to pay attention to possible drug-induced origins of lung disease.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Eosinofilia Pulmonar / Inhibidores Selectivos de la Recaptación de Serotonina / Sertralina Límite: Aged / Humans Idioma: Fr Revista: Rev Mal Respir Año: 2021 Tipo del documento: Article Pais de publicación: Francia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Eosinofilia Pulmonar / Inhibidores Selectivos de la Recaptación de Serotonina / Sertralina Límite: Aged / Humans Idioma: Fr Revista: Rev Mal Respir Año: 2021 Tipo del documento: Article Pais de publicación: Francia